By E. Nieschlag (auth.), Prof. Dr. med., FRCP Eberhard Nieschlag, Prof. Dr. med. Hermann M. Behre (eds.)
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Additional info for Andrology: Male Reproductive Health and Dysfunction
Due to the latest developments of techniques in the field of molecular biology and other areas, we are able to perform artificial inseminations, we are able to determine and to influence the sex of an individual and we will soon, in theory, be even able to treat diseases on the genetic level inside the stern cells. Furthermore, the somatic consequences of inherited diseases, e. , the lack of seminal ducts, may be by-passed by assisted fertilization (see Chap. 17) while the genes for this disease are still transmitted even if they are recessive.
Fluctuations of the sex ratio at birth in Germany from 1872 to 1998. The influence of the two wars is clearly seen. 0 . 7 e. ,-! 2' ing spermatozoa. This is, however, not the case. The vast majority of investigations addressing this topic were unable to identify any marked deviation from 50 % of each sex (Goldman et al. 1993; Lobel et al. 1993). Thus, either the underlying reasons must be found on the female side or the functions of the X- and Y-bearing sperm are subject to infiuence. In fact, the sex ratio at birth is considerably infiuenced by the time of conception (James 1980).
F. Holstein, Institute of Anatomy, Uni· versity of Hamburg) by also the function of its compartments are primarily infiuenced by structures of the hypothalamus and the pituitary gland (endoerine regulation). In addition,loeal control mechanisms (paracrine and autocrine factors) playan important role in the regulation of testicular function. 1 Interstitial Compartment The most important cens of this compartment are the Leydig cens. These cens are the source of testicular test0sterone. Aside from Leydig cens, the interstitial compartment also contains immune cens, blood and lymph vessels, nerves, fibroblasts and loose connective tissue.