Antimicrobial Drugs: Chronicle of a twentieth century by David Greenwood

By David Greenwood

Among 1935 and 1944 the sector of microbiology, and by way of implication drugs as a complete, underwent dramatic development. the invention of the extreme antibacterial houses of sulphonamides, penicillin, and streptomycin caused a frantic hunt for extra antimicrobial medicines that used to be to yield an ample harvest in a really brief house of time. by means of the early Sixties greater than 50 antibacterial brokers have been to be had to the prescribing health care professional and, principally by means of a means of chemical amendment of latest compounds, that quantity has greater than tripled this day. we have now turn into so used to the prepared availability of those quite secure and powerful 'miracle medications' that it's now tough to know how they remodeled the remedy of an infection.

This ebook files the development made up of the 1st tentative look for an elusive 'chemotherapy' of an infection within the early days of the 20 th century, to the improvement of potent antiviral brokers for the administration of HIV because the millennium drew to a detailed. It additionally bargains a party of the contributors and teams that made this miracle occur, in addition to studying the inexorable upward thrust of the worldwide pharmaceutical undefined, and, so much intriguingly, the basic enter of luck.

an infection nonetheless keeps a excessive profile in either medication and the media, with the present threats of 'superbugs' resembling MRSA bought in medical institution, and a possible resistance to antibiotics. This e-book tracks the background of antimicrobial medicinal drugs, a amazing scientific triumph that has supplied medical professionals with an awesome armoury of secure and powerful medications that make sure that reversion to the helpless country of the struggle opposed to an infection witnessed within the early 1900s is very not going. This well timed compendium recognizes the brokers that experience without doubt ended in the comfort of extra human and animal discomfort than the other type of gear within the historical past of clinical endeavour.

Show description

Read Online or Download Antimicrobial Drugs: Chronicle of a twentieth century medical triumph PDF

Similar special topics books

Software Metrics A Guide To Planning, Analysis, And Application

This ebook simplifies software program dimension and explains its price as a device for decision-makers at software program businesses. options awarded in software program Metrics: A consultant to making plans, research, and alertness are derived from top practices. the tips are field-proven, down-to-earth, and easy, making it a useful source for these striving for technique development.

Tiger Bone & Rhino Horn: The Destruction of Wildlife for Traditional Chinese Medicine

In components of Korea and China, moon bears, black yet for the crescent-shaped patch of white on their chests, are captured within the wild and taken to "bear farms" the place they're imprisoned in squeeze cages, and a metal catheter is inserted into their gall bladders. The dripping bile is accumulated as a remedy for diseases starting from an disappointed belly to dermis burns.

Shock Therapy: A History of Electroconvulsive Treatment in Mental Illness

Surprise remedy is making a return this day within the remedy of significant psychological ailment. regardless of its reemergence as a secure and powerful psychiatric instrument, despite the fact that, it is still shrouded by means of a longstanding adverse public photo, now not least because of motion pictures akin to the vintage One Flew over the Cuckoo's Nest, the place the inmate of a psychiatric medical institution (played by way of Jack Nicholson) is subjected to electro-shock to scale back his rebellious habit.

Lasers for medical applications: Diagnostics, therapy and surgery

Lasers became an fundamental clinical software and new thoughts and coverings regarding them are being pioneered for all time. The editor and participants start through the reaction of tissue to laser mild. They then define the categories of lasers utilized in medication, together with solid-state, fuel, dye and semiconductor lasers and speak about using lasers for diagnostics, akin to optical coherence tomography, laser spectroscopy in biomedicine and optical biopsy.

Extra resources for Antimicrobial Drugs: Chronicle of a twentieth century medical triumph

Example text

Among the most important, especially in areas of poor sanitation, is the amoeba that causes amoebic dysentery and amoebic liver abscess, Entamoeba histolytica. More common worldwide, but usually responsible for less serious disease, is the flagellate protozoon, Giardia lamblia, a cause of ‘failure to thrive’ in infants and chronic diarrhoea in all age groups. One of the commonest causes of vaginal discharge in women (and sometimes urethritis in their male consorts) throughout the world is another type of flagellate protozoon called Trichomonas vaginalis.

By the end of the nineteenth century, the germ theory was firmly entrenched, although powerful dissenting voices remained. In Britain, these included the eminent gynaecologist, Lawson Tait (8) and the Cambridge anatomist-turned-historian, Charles Creighton, who notwithstanding his scepticism over the role of germs was able to write a comprehensive, if idiosyncratic, history of epidemic disease in Britain (9). Before we dismiss such historical ‘losers’ as wilfully blind to scientific advance, we should remember that early enthusiasm for the germ theory led to numerous false claims that were the subject of much legitimate dispute.

At the present time, molecular methods of bacterial diagnosis are slowly replacing the time-honoured techniques of microscopy, culture, and identification that established the discipline of medical bacteriology in the late nineteenth century. The change is inevitable, but few of the newer procedures, though ingenious and often adaptable to automation, require the skill and experience demanded by the elegant methods that evolved in the early days of bacteriology. Nor do they provide the intellectual satisfaction of recognizing the characteristic features of individual pathogens under the microscope or on the agar plate.

Download PDF sample

Rated 4.58 of 5 – based on 44 votes