By Michael J. Mann, Ryuichi Morishita (auth.), Grant N. Pierce, William C. Claycomb (eds.)
Experimental concepts are the existence blood of technological know-how. the higher the method is, the extra trustworthy and actual the implications should be. eventually, it will result in a clearer interpretation of these effects and more impregnable conclusions from any set of experiments. Experimental technique within the quarter of cardiovascular biochemistry and molecular biology has complex significantly within the final decade. as a result of those elements, it used to be suggestion targeted factor of Molecular and mobile Biochemistry devoted to the unconventional, most up-to-date technological advances within the box used to be warranted. We needs to thank Dr Naranjan S. Dhalla, Editor-in-Chief of Molecular and CellularBiochemistry, for his willingness to submit a subject matter with this sort of concentration. we've got attracted the various leaders within the box of cardiovascular biology to post articles describing essentially the most novel, major ideas at the moment in use of their laboratories. the aim of the manuscripts used to be to not describe the new experimental findings from each one laboratory as is finished in most traditional manuscripts. as an alternative, the aim of the articles discovered inside of this centred quantity of Molecular and mobile Biochemistry used to be to explain how the strategy is played at the laboratory bench in order that others much less acquainted with the strategy are able to use it of their personal labs. the topics defined during this quantity should be normally subdivided into 3 different types: molecular biology, cellphone biology and easy biochemistry. The tools conceal vast parts together with a number of DNA and RNA expression applied sciences, transfection suggestions, quantification of ion flux circulation, measurements of lipid metabolism, advances within the tradition of particular cardiovascular telephone populations, and using confocal microscopy to envision cellphone constitution and serve as. We thank the entire authors who've contributed loads in their time and efforts and, most significantly, shared the `secrets' of those precious recommendations with the remainder of the cardiovascular learn community.