Glossary of Molecular Biology Terminology (From: Hematology by Kaushansky K.

By Kaushansky K.

This thesaurus is designed lo support ihe reader with the terminology of molecular biology. every year, the thesaurus should be elevated to incorporate new phrases brought within the schooling application. the elemental terminology of molecular biology can be incorporated. The word list is split into a number of common sections. A cross-reference advisor is incorporated to direct readers to the phrases thev have an interest in. The wish is this addition to the schooling software will extra the certainty of these who're much less conversant in the self-discipline of molecular biology.

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Davidson: Yes, that is generally so. Laskey: Is the nucleus continuing to export RNA with the repeats in it, during early embryogenesis? Davidson: Not so far as we can see. REFERENCES Bachvarova R 1981 Synthesis, turnover, and stability of heterogeneous RNA in growing mouse oocytes. Dev Biol 86:384-392 Brandhorst BP, Verma DPS, Fromson D 1979Polyadenylated and nonpolyadenylated messenger RNA fractions from sea urchin embryos code for the same abundant proteins. Dev Biol 71 :128-141 Davidson EH, Britten RJ 1979 Regulation of gene expression: possible role of repetitive sequences.

There are some examples; Dictyostelium RNAs have repeats, at the 5’ ends of many messages (Kimmel & Firtell979, Zuker & Lodish 1981). Also, in the case of clones of mouse histocompatibility genes, the first cDNA clone (pH2-IIa) made by Steinmetz et a1 (1981) has both abundantly repeated DNA sequences and middle repetitive DNA sequences at its 3’ end in the untranslated region. Davidson: The Dictyostelium case is very different from what I have been discussing. Only one strand of the repeat sequence families that have been identified in Dicfyosteliurn is ever represented in the message.

Proc Natl Acad Sci USA 79:2323-2327 Hines PJ, Benbow RM 1982 Initiation of replication at specific origins in DNA molecules microinjected into unfertilized eggs of the frog Xenopus laevis. Cell 30:459-469 Krohne G, Franke WW 1980a Immunological identification and localization of the predominant nuclear protein of the amphibian oocyte nucleus. Proc Natl Acad Sci USA 77:1034-1038 Krohne G , Franke WW 1980b A major soluble acidic protein located in nuclei of diverse vertebrate species. Exp Cell Res 129:167-189 Laskey RA, Harland RM, Earnshaw WE, Dingwall C 1981Chromatin assembly and the coordination of DNA replication in the eukaryotic genome.

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