Histological Studies of the Human Thyroid Gland Observed by Shooichi Sugiyama

By Shooichi Sugiyama

The histological constitution of the thyroid gland is comparatively basic, however the interpretation of the histological photograph of person glands tested isn't constantly effortless. The structural relation is so variable that it is usually tough to figure out even if the gland is inside of common variety or no longer, in order that interpreta. tion has a tendency to beeome roughly subjective and empirie. As said by way of WEGELIN (1926), the adaptation might depend on the attribute nation of the thyroid gland as a ductless gland, heavily akin to an alveolar gland with a accumulating duct approach and amassing colloid within the follicles. The colloid contained will be considerable or searee, based upon the requirement of the animal physique and the depth of secretory stimulation, leading to the development of the parenehyma, specifically the follicles, to be additionally variable. This kingdom is especially exaggerated within the human thyroid gland (HINTON, 1931; BIANCHEDI, 1934; ROSENKRANZ, 1935), and stimulated by way of assorted eomplieated eonditions of person lifestyles, it's comes very tricky to research the histological pietures provided. Notwith status eurrent curiosity within the body structure of the human thyroid gland with regards to pathology and ailment, little paintings has been performed to explain its histology, specially its developmental histology.

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Extra resources for Histological Studies of the Human Thyroid Gland Observed from the Viewpoint of its Postnatal Development

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Formol. Hematoxylin and eosin. a - x 15; b - x 30; c - x 40 (Figs. 13 and 14). During this period the colloid contained in large and mediumsized follicles was moderately eosinophilic and homogeneous. After this period, the colloid decreased in amount gradually with variable staining intensity and concentration (Figs. 15 to 17). 18 to 20). The colloid indicated sometimes slightly increased vacuolation in apart just elose to the Sanderson-Damberg's bolster-like swellings and their relatives, but not always decreased in staining intensity here.

It was feebly eosinophilic, dilute and homogeneous, but showed no increased vacuolation. Further, no significant desquamation of the folliele cells was found in the colloid. Thereafter, the colloid increased in amount with the change of the gland to macrofollicular type (Figs. 7 to 12) and was most abundant from the late stage of early adult Iife to the beginning stage of late adult life Fig. 26a-c. 26 years old man. The nltimobranchial cell cords and cyst appear as a residual part 01 the parathyro(IV)-thymo(IV)-nltimobranchial complex (parathyroid part: PT; thymic part: TM).

Furthermore, yellowish brown pigment granules were contained in the apical zone and as many as or sometimes more than in the follicle cells. The cavities contained granular, sometimes vacuolar, feebly eosinophilic or basophilic material together with several desquamated cells and rarely wandering cells. 6. Colloid Colloid ranged in staining from feebly to moderately eosinophilic, and was homogeneous, and showed a little marginal vacuolation frequently with a central or an eccentrical large vacuole.

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