In Vivo Models of Inflammation, 2e, Vol. II by Christopher S. Stevenson, Lisa A. Marshall, Douglas W.

By Christopher S. Stevenson, Lisa A. Marshall, Douglas W. Morgan

In Vivo versions of irritation (Vol. 2) offers biomedical researchers in either the pharmaceutical and academia with an outline of the cutting-edge animal version structures used to emulate ailments with elements of irritation. This moment variation acts as a supplement to the 1st, describing and updating the normal types which are such a lot applied for particular disorder parts. New types are integrated exploring rising parts of irritation study.

Show description

Read Online or Download In Vivo Models of Inflammation, 2e, Vol. II PDF

Similar nonfiction_4 books

SS: Hitler;s bloody sword

Штурмовые отряды СС. Роль Гитлера в формировании этой мощной нацистской силы. Униформа и методы применения частей СС в тылу и на фронте. Действия Ваффен-СС. В том числе на Восточном фронте. Обо всем этом рассказывается в материалах этого электронного сборника. Материалы написаны ведущими британскими историками, посвятившими истории нацизма и его военной силы не один десяток лет.

Extra resources for In Vivo Models of Inflammation, 2e, Vol. II

Example text

3A–E). The emphysematous lesions in these models are due to increases in alveolar duct area and enlarged alveolar spaces. Fewer studies in rodents have looked at the effect of chronic smoke exposure on small airway structure and function; however, there are a few reports of smoke-induced increases in airway fibrosis and changes in airway function [85–88]. However, while most of the inflammatory and structural alterations in these chronic rodent smoking models are similar to those that occur in chronic smokers, they are subtle changes by comparison to those observed in COPD patients.

J Pharmacol Exp Ther 298: 411–419 Mochizuki A, Tamura N, Yatabe Y, Onodera S, Hiruma T, Inaba N, Kusunoki J, Tomioka H (2001) Suppressive effects of F-1322 on the antigen-induced late asthmatic response and pulmonary eosinophilia in guinea pigs. Eur J Pharmacol 430: 123–133 Leick-Maldonado EA, Kay FU, Leonhardt MC, Kasahara DI, Prado CM, Fernandes FT, Martins MA, Tiberio IF (2004) Comparison of glucocorticoid and cysteinyl leukotriene receptor antagonist treatments in an experimental model of chronic airway inflammation in guinea-pigs.

This keeps the animals free of any respiratory infections that are likely to be a key element in the progression of COPD. 41 Christopher S. Stevenson and David C. Underwood A B C D E Figure 3 Images of lung sections from air-exposed (A and D) and smoke-exposed (B, C, and E) rats. Smoke exposure leads to inflammatory cell aggregates in the alveolar spaces (B), and this is believed to lead to the eventual loss of alveolar integrity (C). Another prominent feature of this model is the thickening of the epithelium and goblet cell metaplasia that occurs after smoke exposure (E).

Download PDF sample

Rated 4.24 of 5 – based on 7 votes