By R.M. Kenedi
Read or Download Perspectives in Biomedical Engineering: Proceedings of a Symposium organised in association with the Biological Engineering Society and held in the University of Strathclyde, Glasgow, June 1972 PDF
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Extra resources for Perspectives in Biomedical Engineering: Proceedings of a Symposium organised in association with the Biological Engineering Society and held in the University of Strathclyde, Glasgow, June 1972
The experiences of the Michigan group when Dr A. Kantrowitz implanted a patch graft to the aorta and used it as an implantable booster heart were unfortunate. Cardiac Assist Devices The inside surface was Dacron fabric, electroconductive polyurethane ('electrolour') and was sutured into the aorta of the patient. After several months of survival this booster heart improved the cardiac condition of the patient, but in the end the patient died of infection. Certainly this is good evidence supporting the use of a totally implantable mechanical device.
If there is a balance sheet, the cost of treating the patient will be set against the patient's theoretical contribution to the Gross National Product. No account will be taken of the cost of allowing a patient to die a chronic death in hospital, of his dependents' costs, his insurance payments, or the less visible loss to the economy due to the loss of payment of insurance premiums and taxes, consumer spending, etc. There is little which can be done to combat this attitudinal climate which compares the new with the theoretical and not with the established.
Such protein can be mixed in a synthetic material as in aldehydetreated albumin, natural rubber coated over plastic or it can be in natural tissue. The treatment described probably makes the protein insoluble, cross-linked or denatured. What kind of process constitutes the main role is not completely understood at present, consequently it is difficult to select an appropriate term to describe it. Thus the term 'biolisation' came into use. Together with this term, a possible process for production of biocompatible (particularly blood compatible) material was also proposed.