By Wolfgang Haupt (auth.), Giuliano Colombetti, Francesco Lenci, Pill-Soon Song (eds.)
This e-book is predicated at the lectures given on the NATO complicated research Institute on "Sensory conception and Transduction in Aneural Organisms" held in Volterra (Pisa. Italy) from the 3rd to the fourteenth of September. 1984. The complex learn Institute was once deliberate as a excessive point path facing numerous points and difficulties of sensory conception and transduction of numerous environmental stimuli in aneural organisms. Scientists from varied fields and cultural backgrounds have been current on the assembly. either as teachers and as scholars. The lectures and the discussions that represented a good built-in interdisci plinary method of the questions thought of. on the finish of the complicated examine Institute direction. it was once particularly transparent that. notwith status the plain heterogeneity of the themes handled. unifying options and concepts already existed, one of the most crucial being the position of membranes and their physicochemical homes. All this could be mirrored within the content material of this publication. We gratefully recognize the monetary sponsorship of the medical Affairs department of NATO (Brussels), that made either the complex examine Institute on "Sensory conception and Transduction in Aneural Organisms" and this publication attainable. eventually. we're additionally indebted to Ms. Pat Parham Morgan who expertly retyped the entire chapters of the ebook and Ms. Leslie Schmidt of Plenum Publishing Co. supplied us necessary suggestion and recommendations at the instruction of this e-book. G. Colombetti F. Lenci P. S.
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Thus, pH sensing and weak-acid sensing are mechanistically rather similar--we can regard the receptor in both instances as a proton sensor. How other repellents operate is unclear (Tso and Adler, 1974). They too perturb the properties of one or more of the MCPs, but it is questionable whether there are binding sites for any given organic repellent, in view of the high concentrations (typically 10 mM or higher) that are required (Oosawa and Imae, 1983). A reasonable guess would be that they are affecting some cellular parameter, say membrane fluidity, and that the sensing protein is responding to that rather than to the chemical compound per ~.
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