Thiol Redox Transitions in Cell Signaling, Part A: Chemistry by Enrique Cadenas, Lester Packer

By Enrique Cadenas, Lester Packer

This quantity, besides its significant other (volume 475), offers tools and protocols facing thiol oxidation-reduction reactions and their implications as they relate to cell signaling. This first installment of Cadenas and Packer's two-volume therapy in particular offers with glutathionylation and dethiolation, and peroxide elimination through peroxiredoxins/thioredoxins and glutathione peroxidases. The seriously acclaimed laboratory normal for 40 years, Methods in Enzymology is among the so much hugely revered guides within the box of biochemistry. considering that 1955, each one quantity has been eagerly awaited, often consulted, and praised via researchers and reviewers alike. Over 450 volumes were released so far, and lots more and plenty of the cloth is suitable even today--truly a necessary booklet for researchers in all fields of existence sciences.

*Along with significant other quantity, presents a whole assessment of innovations essential to the research of thiol redox when it comes to mobilephone signaling
* Gathers attempted and demonstrated ideas from international labs, delivering either new and tried-and-true methods
* appropriate history and reference info given for methods can be utilized as a advisor to constructing protocols in a couple of disciplines

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Thiol Redox Transitions in Cell Signaling, Part A: Chemistry and Biochemistry of Low Molecular Weight and Protein Thiols

This quantity, besides its spouse (volume 475), offers equipment and protocols facing thiol oxidation-reduction reactions and their implications as they relate to cell signaling. This first installment of Cadenas and Packer's two-volume therapy particularly offers with glutathionylation and dethiolation, and peroxide elimination by way of peroxiredoxins/thioredoxins and glutathione peroxidases.

Additional info for Thiol Redox Transitions in Cell Signaling, Part A: Chemistry and Biochemistry of Low Molecular Weight and Protein Thiols

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3. 4. Redoxins 5. 1. 2. 3. 4. 5. 6. Signaling versus defense or modulation of redox signaling by competition 6. Conclusions and Perspectives References 2 3 6 9 9 14 17 17 19 20 21 23 24 24 26 27 28 Abstract The history of free radical biochemistry is briefly reviewed in respect to major trend shifts from the focus on radiation damage toward enzymology of radical production and removal and ultimately the role of radicals, hydroperoxides, and related fast reacting compounds in metabolic regulation.

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