UHMWPE Biomaterials Handbook. Ultra-High Molecular Weight by Steven M. Kurtz

By Steven M. Kurtz

This ebook describes the technology, improvement, houses and alertness of of ultra-high molecular weight polyethylene (UHMWPE) utilized in man made joints. This fabric is at present utilized in 1.4 million sufferers worldwide each year to be used within the hip, knee, top extremities, and backbone.

Since the ebook of the first version there were significant advances within the improvement and scientific adoption of hugely crosslinked UHMWPE for hip and knee alternative. There has additionally been an immense foreign attempt to introduce diet E stabilized UHMWPE for sufferers. The amassed wisdom on those periods of fabrics are a key function of the 2d version, in addition to an extra 19 extra chapters offering assurance of the foremost engineering facets (biomechanical and fabrics technology) and clinical/biological functionality of UHMWPE, delivering a extra whole reference for commercial and educational fabrics experts, and for surgeons and clinicians who require an figuring out of the biomaterials homes of UHMWPE to paintings effectively on sufferer applications.

* The UHMWPE instruction manual is the great reference for pros, researchers, and clinicians operating with biomaterials applied sciences for joint substitute * New to this variation: 19 new chapters continue readers brand new with this fast paced subject, together with a brand new part on UHMWPE biomaterials; hugely crosslinked UHMWPE for hip and knee alternative; nutrition E stabilized UHMWPE for sufferers; scientific functionality, tribology an biologic interplay of UHMWPE * cutting-edge insurance of UHMWPE expertise, orthopedic functions, biomaterial characterisation and engineering elements from acknowledged leaders within the field

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Sample text

Wroblewski, who started his service at Wrightington in 1967, the UHMWPE cups were 39 Chapter | 4 The Origins of UHMWPE in Total Hip Arthroplasty chemically sterilized by wrapping them in gauze and soaking them in Cidex (glutaraldehyde) overnight. Although UHMWPE cups produced commercially by Thackray were gamma irradiated starting in 1968 [21], it remains unclear based upon the documents available today, when, prior to 1968, gamma irradiation was initiated for cups that were implanted at Wrightington [21].

However, there was clearly a respect for the talents of the surgeon for the engineer, and vice versa. Mutual respect, collaboration, as well as genuine talent, were the necessary foundations to achieve the breakthrough for joint arthroplasty which was desperately needed. The remarkable clinical performance of UHMWPE following its introduction is recounted in the following chapter. 13 Acknowledgments This chapter would not have been possible without the assistance of many supportive colleagues in England.

Charnley realized that an artificial joint fabricated from synthetic materials like metal or plastic could not operate with purely hydrodynamic lubrication. In 1959, Charnley wrote that “attempts to lubricate any artificial joint must be based on the idea of using boundary lubrication. ” Therefore, friction, not wear, was Charnley’s primary reason for selecting PTFE. From the onset, Charnley’s artificial joint design was based on the principles of boundary lubrication, during which pressure in the synovial fluid is not sufficient to fully separate the joint surfaces for load bearing.

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